What is Role of P53 Gene in Cancer? « CancerWORLD Cancer Treatment Research Journal - p53 gene and breast cancer

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Discover the P53 Gene that Controls Cancer Development p53 gene and breast cancer


Apr 01, 2002 · p53 mutation remains the most common genetic change identified in human neoplasia. In breast cancer, p53 mutation is associated with more aggressive disease and worse overall survival. The frequency of mutation in p53 is, however, lower in breast cancer than in other solid tumours.Cited by: 337.

The p53 gene (TP53) is a gene that is mutated in many cancers, and is the most common gene mutation found in cancer cells. The gene is a type of tumor suppressor gene that codes for a protein that inhibits the development and growth of tumors.

Feb 12, 2002 · p53 mutation remains the most common genetic change identified in human neoplasia. In breast cancer, p53 mutation is associated with more aggressive disease and worse overall survival. The frequency of mutation in p53 is, however, lower in breast cancer than in other solid tumours.Cited by: 337.